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Both CDCA and deoxycholic acid (DCA) demonstrate positive inotropic effects (enhanced LVDP, dp/dt max, muscle strip tension) and negative chronotropic effects in isolated rat hearts via calcium-dependent mechanisms (Gao et al., 2021)

doi: 10.1111/j.1399-3054.1997.tb01025.x 46 CharbonnierP.ChovelonB.RaveletC.NgoT

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EMBO Mol Med 2:429439